With everything else checked, deleted, and adjusted, you can safely save your file with the model in the screen orientation you want for its thumbnail. Before you upload it, a good test for correct behavior is in order.
In a new SketchUp file, import your model and check the following:
- Does the thumbnail look correct?
- If designed to interact with existing geometry, is it attaching to other faces as intended?
- If it is a free standing model or component, does it insert at the desired point?
- Select the imported model or component. Is the bounding box tight to the geometry?
- Can you use the Move tool to interact with the component?
- Can you apply Materials?
- Can you edit the component easily?
Once you’ve answered these questions you can upload your model!